Tracking Human Population History: The Role of MSMC and MSMC2 1. Introduction
: Convert raw genomic data into VCF and mask files. Combine Samples : Aggregate data from multiple individuals. Download MSMC Maps from Here (Click on this text)
) : The primary purpose of MSMC is to estimate the inverse of the coalescence rate, which can be interpreted as the Necap N sub e over time. Tracking Human Population History: The Role of MSMC
Researchers typically follow a multi-step pipeline available on platforms like GitHub (stschiff/msmc) : typically one per chromosome
: The model requires several input files, typically one per chromosome, containing segregating sites and information on "called" sites.