[s4e2] Love/addiction May 2026

George struggles with his guilt after admitting he loves Izzie, while Callie, as Chief Resident, is overwhelmed by her duties and her suspicions that George is cheating.

Meredith's half-sister, Lexie, attempts to bond with Meredith, who remains resistant to having a relationship with her. [S4E2] Love/Addiction

The residents and interns treat victims of a massive apartment fire caused by a meth lab explosion. Alex Karev deals with a particularly difficult case involving a baby who suffered a stroke due to the meth lab environment. George struggles with his guilt after admitting he

Watch a recap of the episode's themes and major character developments here: as Chief Resident

is the second episode of the fourth season of the medical drama series Grey's Anatomy .