Large groups can hinder the approach of the diene, often dictating which face of the quinone is attacked.
) on the quinone accelerate the reaction by lowering the LUMO energy. reactions of substituted quinones
If the quinone has a good leaving group (like a halogen in p-chloranil ), a nucleophile can displace it directly. This is a common route for synthesizing complex dyes and bioactive molecules. 5. Photochemical Reactions Large groups can hinder the approach of the
This is the most common reaction for substituted quinones. A nucleophile (like an amine, thiol, or alcohol) attacks the double bond. or alcohol) attacks the double bond.