Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow
Researchers use PearlCAM to test new "smart" dyes that attach specifically to cancer cells. By viewing the animal through the Pearl system, surgeons can practice identifying tumor margins that would be invisible to the naked eye. Washington University has utilized this for foundations in translational imaging. 2. Drug Delivery Tracking PearlCAM
The workflow for a research team using PearlCAM typically follows three stages: Because the imaging is non-invasive, researchers can scan
A fluorescent probe (like IRDye®) is injected into the subject. By viewing the animal through the Pearl system,
Before a new cancer drug or imaging agent can be tested on humans, it must be proven effective and safe in animal models. Systems like the LI-COR Pearl Trilogy provide the high-quality data required by regulatory bodies (like the FDA) to move a discovery from the lab to the clinic.
The system is a staple in laboratories focusing on translational medicine. Key use cases include: 1. Fluorescence-Guided Surgery