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The Virtuous Galleria mellonella Model for Scientific ... - PMC

: Newer papers highlight its excellence in studying fungal infections and evaluating the effectiveness of new antifungal drug candidates. Gtlela

: Despite being an insect, its innate immune system shows remarkable similarities to that of mammals, including specialized cells (hemocytes) that function like human neutrophils. The Virtuous Galleria mellonella Model for Scientific

: It allows researchers to follow the "3Rs" principle (Replacement, Reduction, and Refinement) by replacing vertebrate animals in early-stage studies. : It allows researchers to follow the "3Rs"

: Because these larvae were historically sold as reptile food, recent research focuses on standardizing laboratory breeding to ensure reproducible results across different global labs.

: A comprehensive review on Galleria mellonella as a Model for the Study of aPDT discusses how it's used to test light-based therapies (antimicrobial photodynamic therapy) against drug-resistant "superbugs".