Grey's | Anatomy S16e16

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction

The central twist of the episode is that Alex has reunited with his ex-wife, .

He discovered that Izzie used the embryos they froze years ago when she had cancer. Grey's Anatomy s16e16

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins

Alex claims that while he still loves Jo , he cannot bear to let his children grow up without a father the way he did. He is now living on a farm in Kansas where Izzie works as a surgical oncologist. ⚡ Secondary Storylines After reading the letter and realizing her marriage

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex

Alex explains she will always be "his person," but he found a reason to stay away that he couldn't ignore. He expresses his gratitude for their mentorship over

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s.