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Understanding how dendritic spines change size helps researchers decipher the brain's "wiring" and how it stores information. Disruptions in this structural plasticity are often linked to various neurological and cognitive disorders.

The study investigates the role of specific proteins, including CaMKII (Calmodulin-dependent protein kinase II) and actinin , in managing the structural integrity and growth of the dendritic spine. Download 91566

Supplemental information, including data sets and molecular models, is also available for download on the same page. Synapses: Changing the size of dendritic spines - eLife Dendritic spines are tiny protrusions on neurons that

Use the button typically located at the top right of the page to save the PDF directly. 2. Key Findings

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Dendritic spines are tiny protrusions on neurons that receive input from other cells. Their size is a direct physical indicator of —larger spines generally correlate with stronger connections. This report examines how these structures change size (structural plasticity), which is a fundamental process underlying learning and memory. 2. Key Findings