Atopy · Limited Time
The core of atopy is a Type I hypersensitivity reaction driven by a Type 2 immune response.
: Systemic immune priming eventually leads to upper and lower airway inflammation. 3. Key Management Strategies The core of atopy is a Type I
: Often the first sign in infancy, caused by skin barrier defects (e.g., filaggrin mutations) that allow for epicutaneous allergen sensitization. caused by skin barrier defects (e.g.
While there is currently no cure, management focuses on controlling inflammation and restoring barrier function. Atopy - StatPearls - NCBI Bookshelf - NIH activating TH2 or ILC2 cells.
: Antigen-presenting cells perceive allergens (like pollen or dust mites) as danger signals, activating TH2 or ILC2 cells.