The phrase most commonly refers to the Season 5 finale of Grey’s Anatomy (Season 5, Episode 24), which is widely regarded by fans and critics as one of the most emotional and shocking episodes in television history.

A 2022 strategy game by Ryan Laukat, set in the fantasy world of Arzium.

: A contemporary novel focused on themes of motherhood and self-discovery. Reviewers at OnlineBookClub.org describe it as a "thought-provoking narrative" about a woman reclaiming her identity within a marriage. 4. Now or Never (Music) The 4 Squares Review - Now or Never

: Players travel a map, fight monsters, and rebuild their ancestral village over six rounds. It is noted for its "asymmetrical characters" and a robust Story Mode that adds depth to the mechanics.

Depending on your interest, here is a review of that episode and other notable works with the same title: 1. Grey’s Anatomy : Season 5, Episode 24 ("Now or Never")

: It received widespread acclaim, particularly for Katherine Heigl’s performance. Viewers often describe it as "prime time television at its best" due to its brilliant acting and perfect execution. 2. Now or Never (Board Game)

: The episode’s climax occurs when the "John Doe" traces "007"—George O'Malley's nickname—into Meredith’s hand, revealing his true identity just as both he and Izzie begin to flatline.